{"id":1602,"date":"2025-03-19T18:52:42","date_gmt":"2025-03-19T18:52:42","guid":{"rendered":"https:\/\/www.activatebiosciences.com\/?page_id=1602"},"modified":"2025-03-28T11:03:28","modified_gmt":"2025-03-28T11:03:28","slug":"our-technology","status":"publish","type":"page","link":"https:\/\/www.activatebiosciences.com\/index.php\/our-technology\/","title":{"rendered":"Our Technology"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"1602\" class=\"elementor elementor-1602\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-730ec8b animated-slow e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"730ec8b\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;animation&quot;:&quot;fadeIn&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-f1dc94a e-con-full animated-slow e-flex e-con e-child\" data-id=\"f1dc94a\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;none&quot;,&quot;animation_delay&quot;:1300}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3180ef6 elementor-widget-divider--view-line_text elementor-widget-divider--element-align-right animated-slow elementor-widget elementor-widget-divider\" data-id=\"3180ef6\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;none&quot;,&quot;_animation_delay&quot;:1000}\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t\t<span class=\"elementor-divider__text elementor-divider__element\">\n\t\t\t\tOur Technology\t\t\t\t<\/span>\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3919ebc elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"3919ebc\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;none&quot;,&quot;_animation_delay&quot;:700}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Activate. Target. Conquer.<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b27f43f elementor-widget elementor-widget-text-editor\" data-id=\"b27f43f\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;none&quot;,&quot;_animation_delay&quot;:700}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Our first-in-class B cell-based vaccine delivery platform is challenging the standard paradigm of vaccine delivery, ensuring that cancer vaccines <u>GET IN<\/u> and <u>GET GOING<\/u>!<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ce838aa elementor-align-center animated-slow elementor-widget elementor-widget-button\" data-id=\"ce838aa\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;none&quot;,&quot;_animation_delay&quot;:1000}\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm elementor-animation-grow\" href=\"#explore\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-far-arrow-alt-circle-right\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M504 256C504 119 393 8 256 8S8 119 8 256s111 248 248 248 248-111 248-248zm-448 0c0-110.5 89.5-200 200-200s200 89.5 200 200-89.5 200-200 200S56 366.5 56 256zm72 20v-40c0-6.6 5.4-12 12-12h116v-67c0-10.7 12.9-16 20.5-8.5l99 99c4.7 4.7 4.7 12.3 0 17l-99 99c-7.6 7.6-20.5 2.2-20.5-8.5v-67H140c-6.6 0-12-5.4-12-12z\"><\/path><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Get Started<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-861e861 animated-slow e-flex e-con-boxed e-con e-parent\" data-id=\"861e861\" data-element_type=\"container\" data-e-type=\"container\" id=\"explore\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;animation&quot;:&quot;none&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-d2f9273 e-con-full e-flex e-con e-child\" data-id=\"d2f9273\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;none&quot;,&quot;animation_delay&quot;:0}\">\n\t\t<div class=\"elementor-element elementor-element-3fac678 e-con-full e-flex e-con e-child\" data-id=\"3fac678\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-11139df elementor-widget elementor-widget-heading\" data-id=\"11139df\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">We're doing cancer vaccines different...<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4ec4b52 elementor-widget elementor-widget-text-editor\" data-id=\"4ec4b52\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Normally, when a vaccine is administered, while the initial immune response is crucial, the main goal is to produce memory cells that can act on a <b>future infection<\/b>.<\/p>\n<p>With a cancer vaccine, things are a bit different &#8211; they are typically given to a cancer patient and must work to induce an <b>immediate immune-mediated therapeutic effect<\/b> as well as immune memory &#8211; a significant distinction.<\/p>\n<p>Our B cell-based vaccine delivery platform is unlike any vaccine you&#8217;ve seen before. It is designed explicitly to overcome the major challenges and finally deliver on the promise of cancer vaccines.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e4c2c64 elementor-widget elementor-widget-button\" data-id=\"e4c2c64\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm elementor-animation-grow\" href=\"#vaccine-technology\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-far-arrow-alt-circle-right\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M504 256C504 119 393 8 256 8S8 119 8 256s111 248 248 248 248-111 248-248zm-448 0c0-110.5 89.5-200 200-200s200 89.5 200 200-89.5 200-200 200S56 366.5 56 256zm72 20v-40c0-6.6 5.4-12 12-12h116v-67c0-10.7 12.9-16 20.5-8.5l99 99c4.7 4.7 4.7 12.3 0 17l-99 99c-7.6 7.6-20.5 2.2-20.5-8.5v-67H140c-6.6 0-12-5.4-12-12z\"><\/path><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Learn More<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0ba1c93 e-con-full e-flex e-con e-child\" data-id=\"0ba1c93\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b1ee86a elementor-widget__width-initial elementor-invisible elementor-widget elementor-widget-image\" data-id=\"b1ee86a\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInRight&quot;}\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"667\" height=\"560\" src=\"https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Screenshotff-2025-03-17-174723.png\" class=\"attachment-full size-full wp-image-1306\" alt=\"\" srcset=\"https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Screenshotff-2025-03-17-174723.png 667w, https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Screenshotff-2025-03-17-174723-300x252.png 300w\" sizes=\"(max-width: 667px) 100vw, 667px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c53ef76 e-flex e-con-boxed e-con e-parent\" data-id=\"c53ef76\" data-element_type=\"container\" data-e-type=\"container\" id=\"vaccine-technology\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-16487bf e-con-full e-flex e-con e-child\" data-id=\"16487bf\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1180bdd elementor-widget elementor-widget-heading\" data-id=\"1180bdd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Our Approach to Cancer Vaccines<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1526381 elementor-widget elementor-widget-text-editor\" data-id=\"1526381\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>It&#8217;s not that traditional vaccines are BAD &#8211; they&#8217;re very good at what they do &#8211; it&#8217;s just that, they&#8217;re not really designed to fight cancer. So, we need to analyze how vaccines are designed to work and then optimize the approach for cancer.\u00a0<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-47d36e1 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"47d36e1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-27cf55e e-n-tabs-mobile elementor-widget elementor-widget-n-tabs\" data-id=\"27cf55e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"nested-tabs.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"e-n-tabs\" data-widget-number=\"41743710\" aria-label=\"Tabs. Open items with Enter or Space, close with Escape and navigate using the Arrow keys.\">\n\t\t\t<div class=\"e-n-tabs-heading\" role=\"tablist\">\n\t\t\t\t\t<button id=\"e-n-tab-title-417437101\" data-tab-title-id=\"e-n-tab-title-417437101\" class=\"e-n-tab-title\" aria-selected=\"true\" data-tab-index=\"1\" role=\"tab\" tabindex=\"0\" aria-controls=\"e-n-tab-content-417437101\" style=\"--n-tabs-title-order: 1;\">\n\t\t\t\t\t\t<span class=\"e-n-tab-title-text\">\n\t\t\t\tThe Foundation\t\t\t<\/span>\n\t\t<\/button>\n\t\t\t\t<button id=\"e-n-tab-title-417437102\" data-tab-title-id=\"e-n-tab-title-417437102\" class=\"e-n-tab-title\" aria-selected=\"false\" data-tab-index=\"2\" role=\"tab\" tabindex=\"-1\" aria-controls=\"e-n-tab-content-417437102\" style=\"--n-tabs-title-order: 2;\">\n\t\t\t\t\t\t<span class=\"e-n-tab-title-text\">\n\t\t\t\tThe Limitations\t\t\t<\/span>\n\t\t<\/button>\n\t\t\t\t<button id=\"e-n-tab-title-417437103\" data-tab-title-id=\"e-n-tab-title-417437103\" class=\"e-n-tab-title\" aria-selected=\"false\" data-tab-index=\"3\" role=\"tab\" tabindex=\"-1\" aria-controls=\"e-n-tab-content-417437103\" style=\"--n-tabs-title-order: 3;\">\n\t\t\t\t\t\t<span class=\"e-n-tab-title-text\">\n\t\t\t\tOur Approach\t\t\t<\/span>\n\t\t<\/button>\n\t\t\t\t<button id=\"e-n-tab-title-417437104\" data-tab-title-id=\"e-n-tab-title-417437104\" class=\"e-n-tab-title\" aria-selected=\"false\" data-tab-index=\"4\" role=\"tab\" tabindex=\"-1\" aria-controls=\"e-n-tab-content-417437104\" style=\"--n-tabs-title-order: 4;\">\n\t\t\t\t\t\t<span class=\"e-n-tab-title-text\">\n\t\t\t\tThe Result\t\t\t<\/span>\n\t\t<\/button>\n\t\t\t\t\t<\/div>\n\t\t\t<div class=\"e-n-tabs-content\">\n\t\t\t\t<div id=\"e-n-tab-content-417437101\" role=\"tabpanel\" aria-labelledby=\"e-n-tab-title-417437101\" data-tab-index=\"1\" style=\"--n-tabs-title-order: 1;\" class=\"e-active elementor-element elementor-element-d309ff5 e-con-full e-flex e-con e-child\" data-id=\"d309ff5\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-8630a9a e-flex e-con-boxed e-con e-child\" data-id=\"8630a9a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e510d00 elementor-widget elementor-widget-image\" data-id=\"e510d00\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1500\" height=\"600\" src=\"https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Activate-Bio-Traditional-Vaccine-Technology-1.png\" class=\"attachment-full size-full wp-image-1796\" alt=\"\" srcset=\"https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Activate-Bio-Traditional-Vaccine-Technology-1.png 1500w, https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Activate-Bio-Traditional-Vaccine-Technology-1-300x120.png 300w, https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Activate-Bio-Traditional-Vaccine-Technology-1-1024x410.png 1024w, https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Activate-Bio-Traditional-Vaccine-Technology-1-768x307.png 768w\" sizes=\"(max-width: 1500px) 100vw, 1500px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c5b0415 elementor-widget elementor-widget-text-editor\" data-id=\"c5b0415\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>In order for a cancer vaccine to elicit an immune response, it must do two things: i) be taken up by a specialized cell type called a dendritic cell (DC), and ii) stimulate the maturation of that DC. Once this happens, the matured, vaccine-loaded DCs will then use the vaccine components to prime and activate T cells. These T cells will go on to induce the proper immunological response.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div id=\"e-n-tab-content-417437102\" role=\"tabpanel\" aria-labelledby=\"e-n-tab-title-417437102\" data-tab-index=\"2\" style=\"--n-tabs-title-order: 2;\" class=\" elementor-element elementor-element-8b88496 e-con-full e-flex e-con e-child\" data-id=\"8b88496\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-5d89513 e-flex e-con-boxed e-con e-child\" data-id=\"5d89513\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e5e710f elementor-widget elementor-widget-heading\" data-id=\"e5e710f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Failure to <b><u>GET IN<\/u><\/b><\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ec4efbb elementor-widget elementor-widget-image\" data-id=\"ec4efbb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1835\" height=\"2055\" src=\"https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/failure_to_get_in-1.png\" class=\"attachment-full size-full wp-image-1791\" alt=\"\" srcset=\"https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/failure_to_get_in-1.png 1835w, https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/failure_to_get_in-1-268x300.png 268w, https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/failure_to_get_in-1-914x1024.png 914w, https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/failure_to_get_in-1-768x860.png 768w, https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/failure_to_get_in-1-1372x1536.png 1372w, https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/failure_to_get_in-1-1829x2048.png 1829w\" sizes=\"(max-width: 1835px) 100vw, 1835px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b735b4d elementor-widget elementor-widget-text-editor\" data-id=\"b735b4d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Traditional vaccines often fail to effectively reach dendritic cells in sufficient concentrations &#8211; in other words, they can&#8217;t <b><u>GET IN<\/u><\/b>. This challenge stems from multiple sources that all result in much of the injected vaccine being either degraded or secreted before ever reaching their target, reducing vaccine efficacy.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a4e536a e-flex e-con-boxed e-con e-child\" data-id=\"a4e536a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3f8deae elementor-widget elementor-widget-heading\" data-id=\"3f8deae\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Failure to <b><u>GET GOING<\/u><\/b><\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d1f736a elementor-widget elementor-widget-image\" data-id=\"d1f736a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1604\" height=\"1711\" src=\"https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/failure-to-get-going.png\" class=\"attachment-full size-full wp-image-1792\" alt=\"\" srcset=\"https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/failure-to-get-going.png 1604w, https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/failure-to-get-going-281x300.png 281w, https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/failure-to-get-going-960x1024.png 960w, https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/failure-to-get-going-768x819.png 768w, https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/failure-to-get-going-1440x1536.png 1440w\" sizes=\"(max-width: 1604px) 100vw, 1604px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8ccd3cd elementor-widget elementor-widget-text-editor\" data-id=\"8ccd3cd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Even when vaccines successfully reach dendritic cells, they frequently lack the necessary co-stimulatory signals to induce full dendritic cell maturation &#8211; in other words, they can&#8217;t really <span style=\"text-decoration: underline;\"><strong>GET GOING<\/strong><\/span>. This results in inadequate T cell priming, leading to weak immune responses.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div id=\"e-n-tab-content-417437103\" role=\"tabpanel\" aria-labelledby=\"e-n-tab-title-417437103\" data-tab-index=\"3\" style=\"--n-tabs-title-order: 3;\" class=\" elementor-element elementor-element-a769e45 e-con-full e-flex e-con e-child\" data-id=\"a769e45\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-488eaca e-flex e-con-boxed e-con e-child\" data-id=\"488eaca\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7bcb6f2 elementor-widget elementor-widget-image\" data-id=\"7bcb6f2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"2274\" height=\"1461\" src=\"https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Activate-Bio-B-cell-vaccine-delivery.png\" class=\"attachment-full size-full wp-image-1828\" alt=\"\" srcset=\"https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Activate-Bio-B-cell-vaccine-delivery.png 2274w, https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Activate-Bio-B-cell-vaccine-delivery-300x193.png 300w, https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Activate-Bio-B-cell-vaccine-delivery-1024x658.png 1024w, https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Activate-Bio-B-cell-vaccine-delivery-768x493.png 768w, https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Activate-Bio-B-cell-vaccine-delivery-1536x987.png 1536w, https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Activate-Bio-B-cell-vaccine-delivery-2048x1316.png 2048w\" sizes=\"(max-width: 2274px) 100vw, 2274px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-39c1ea1 elementor-widget elementor-widget-text-editor\" data-id=\"39c1ea1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>We have developed a B cell cancer vaccine delivery platform that leverages the natural antigen presenting abilities of B cells to promote quick and robust vaccine-mediated anti-cancer responses. Our B cells are loaded with cancer-associated peptides and infused into a cancer patient where they travel to lymphoid organs, deliver the peptides to DCs (<b>GET IN<\/b>) and provide co-stimulatory signaling to ensure DCs can properly engage T cells (<b>GET GOING<\/b>).<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div id=\"e-n-tab-content-417437104\" role=\"tabpanel\" aria-labelledby=\"e-n-tab-title-417437104\" data-tab-index=\"4\" style=\"--n-tabs-title-order: 4;\" class=\" elementor-element elementor-element-bc36232 e-con-full e-flex e-con e-child\" data-id=\"bc36232\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-ef59058 e-flex e-con-boxed e-con e-child\" data-id=\"ef59058\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6ad6cbc elementor-widget elementor-widget-heading\" data-id=\"6ad6cbc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Personalized Cell-Based Cancer Vaccine<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-35a8fcc elementor-widget elementor-widget-image\" data-id=\"35a8fcc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"2177\" height=\"1311\" src=\"https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Activate-Bio-The-Result.png\" class=\"attachment-full size-full wp-image-1952\" alt=\"\" srcset=\"https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Activate-Bio-The-Result.png 2177w, https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Activate-Bio-The-Result-300x181.png 300w, https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Activate-Bio-The-Result-1024x617.png 1024w, https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Activate-Bio-The-Result-768x462.png 768w, https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Activate-Bio-The-Result-1536x925.png 1536w, https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Activate-Bio-The-Result-2048x1233.png 2048w\" sizes=\"(max-width: 2177px) 100vw, 2177px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-cc043c2 elementor-widget elementor-widget-text-editor\" data-id=\"cc043c2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>This results in a highly personalized, modular, cell-based cancer vaccine delivery platform that is able to both fight cancer immediately and provide long-term protection from recurrence in a wide array of patients.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a5342e2 elementor-absolute elementor-hidden-mobile elementor-widget elementor-widget-text-editor\" data-id=\"a5342e2\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_position&quot;:&quot;absolute&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Tabs:<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-cfe7418 e-flex e-con-boxed e-con e-parent\" data-id=\"cfe7418\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b8fdda0 elementor-widget elementor-widget-heading\" data-id=\"b8fdda0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">How It's Done...<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b86cade e-con-full e-flex e-con e-child\" data-id=\"b86cade\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-69724a4 e-con-full e-flex e-con e-child\" data-id=\"69724a4\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d4db047 elementor-widget elementor-widget-text-editor\" data-id=\"d4db047\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p class=\"my-0\">Our personalized B cell-based vaccine platform follows a highly optimized, streamlined process:<\/p><ol class=\"marker:text-textOff list-decimal\"><li><p class=\"my-0\"><b>Acquire B cells<\/b>: We obtain B cells either from the patient (autologous) or from a healthy donor (allogeneic).<\/p><\/li><li><p class=\"my-0\"><b>Incubate and expand<\/b>: The B cells are incubated with a proprietary cocktail containing patient disease-specific antigen peptides, ensuring robust expansion and efficient uptake of vaccine components.<\/p><\/li><li><p class=\"my-0\"><b>Generate vaccine-loaded B cells:<\/b> This process results in a large population of activated, peptide-loaded B cells primed for delivery.<\/p><\/li><li><p class=\"my-0\"><b>Infuse at point of care<\/b>: The prepared B cell vaccine is administered to the patient intravenously.<\/p><\/li><\/ol><p class=\"my-0\">This entire process, from B cell acquisition to patient infusion, is completed within 8-10 days, offering a relatively rapid turnaround for personalized cancer vaccine therapy.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-804e323 e-con-full e-flex e-con e-child\" data-id=\"804e323\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9aab11e image elementor-widget elementor-widget-image\" data-id=\"9aab11e\" data-element_type=\"widget\" data-e-type=\"widget\" id=\"image\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"3149\" height=\"2021\" src=\"https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Manufacturing_image_41.png\" class=\"attachment-full size-full wp-image-1930\" alt=\"\" srcset=\"https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Manufacturing_image_41.png 3149w, https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Manufacturing_image_41-300x193.png 300w, https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Manufacturing_image_41-1024x657.png 1024w, https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Manufacturing_image_41-768x493.png 768w, https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Manufacturing_image_41-1536x986.png 1536w, https:\/\/www.activatebiosciences.com\/wp-content\/uploads\/2025\/03\/Manufacturing_image_41-2048x1314.png 2048w\" sizes=\"(max-width: 3149px) 100vw, 3149px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Our Technology Activate. Target. Conquer. Our first-in-class B cell-based vaccine delivery platform is challenging the standard paradigm of vaccine delivery, ensuring that cancer vaccines GET IN and GET GOING! Get Started We&#8217;re doing cancer vaccines different&#8230; Normally, when a vaccine is administered, while the initial immune response is crucial, the main goal is to produce [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"footnotes":""},"class_list":["post-1602","page","type-page","status-publish","hentry"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/www.activatebiosciences.com\/index.php\/wp-json\/wp\/v2\/pages\/1602","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.activatebiosciences.com\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.activatebiosciences.com\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.activatebiosciences.com\/index.php\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.activatebiosciences.com\/index.php\/wp-json\/wp\/v2\/comments?post=1602"}],"version-history":[{"count":262,"href":"https:\/\/www.activatebiosciences.com\/index.php\/wp-json\/wp\/v2\/pages\/1602\/revisions"}],"predecessor-version":[{"id":2205,"href":"https:\/\/www.activatebiosciences.com\/index.php\/wp-json\/wp\/v2\/pages\/1602\/revisions\/2205"}],"wp:attachment":[{"href":"https:\/\/www.activatebiosciences.com\/index.php\/wp-json\/wp\/v2\/media?parent=1602"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}